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Article

Widely metastatic glioblastoma with BRCA1 and ARID1A mutations: a case report.

BMC cancer - 20 Jan 2020

Umphlett Melissa, Shea Stephanie, Tome-Garcia Jessica, Zhang Yizhou, Hormigo Adilia, Fowkes Mary, Tsankova Nadejda M, Yong Raymund L

Abstract excerpt

BACKGROUND: Glioblastoma (GBM) is a highly malignant brain neoplasm with poor survival. Despite its aggressive nature, metastatic spread of GBM is identified only rarely. While the molecular alterations associated with GBM and its subtypes are well-described, there remains a gap in understanding which alterations may predispose towards metastasis. In this report, we present a case of GBM with multi-organ...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 31959133
DOI: 10.1186/s12885-020-6540-1
PMCID: PMC6971940

Genes

ARID1A
BRCA1
MGMT

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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