Article
Correlation of somatic mutation and expression identifies genes important in human glioblastoma progression and survival.
Cancer research - 1 Jul 2011
Masica David L, Karchin Rachel
Abstract excerpt
Cooperative dysregulation of gene sequence and expression may contribute to cancer formation and progression. The Cancer Genome Atlas (TCGA) Network recently catalogued gene sequence and expression data for a collection of glioblastoma multiforme (GBM) tumors. We developed an automated, model-free method to rapidly and exhaustively examine the correlation among somatic mutation and gene expression and...
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