Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

ARID1A mutations in cancer development: mechanism and therapy.

Carcinogenesis - 27 May 2023

Zhang Xuewei, Zhang Yixuan, Zhao Jinyi, Wu Yinjie, Zhang Na, Shen Wenjing

Abstract excerpt

AT-Rich Interaction Domain 1A (ARID1A) is an important SWItch/Sucrose Non-Fermentation (SWI/SNF) chromatin remodeling complex subunit, and its coding gene has a high mutation frequency in many cancers. Current studies have reported that ARID1A mutational status is correlated to cancer development, including cell proliferation, invasiveness, metastasis, and morphological alterations. ARID1A acts as a tumor...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Mechanisms and Therapy
Share to Chromatin Remodeling and Cancer
Share to DNA-Binding Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mutation

Share to Neoplasms

Share to Nuclear Proteins

Share to Transcription Factors

Share to Tumor Microenvironment

Source

Identifiers

PMID: 36882165
DOI: 10.1093/carcin/bgad011

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

ARID1A mutations in cancer development: mechanism and therapy.PMID 36882165Read ↗

The Role of ARID1A in Tumors: Tumor Initiation or Tumor Suppression?Semantic proximity Read ↗

Roles of ARID1A variations in colorectal cancer: a collaborative reviewSemantic proximity Read ↗

The Role of the AT-Rich Interaction Domain 1A Gene (ARID1A) in Human Carcinogenesis.Semantic proximity Read ↗

The effects of ARID1A mutation in gastric cancer and its significance for treatmentSemantic proximity Read ↗

ARID1A in cancer: Friend or foe?Semantic proximity Read ↗

Recent advances in the ARID family: focusing on roles in human cancerSemantic proximity Read ↗

Remodeling of the ARID1A tumor suppressor.Semantic proximity Read ↗

ARID1A and Its Impact Across the Hallmarks of CancerSemantic proximity Read ↗

The emerging roles of ARID1A in tumor suppression.Semantic proximity Read ↗

ARID1A mutations in lung cancer: biology, prognostic role, and therapeutic implications.Semantic proximity Read ↗

ARID1A loss in cancer: Towards a mechanistic understanding.Semantic proximity Read ↗

ARID1A Mutation in Metastatic Breast Cancer: A Potential Therapeutic TargetSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.