Article

Common Substrates of Early Illness Severity: Clinical, Genetic, and Brain Evidence

2026-04-22

Abstract excerpt

<h4>Background</h4> The severity of positive psychotic symptoms largely defines emerging psychosis syndromes. However, depressive and negative symptoms are strongly psychologically and biologically interlinked. A transdiagnostic exploration of symptom severity across early illness syndromes could enhance the understanding of shared common factors and future trajectories of mental illness. We aimed to identify sub...

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Literature Corpus work: bca57abd-14b2-518b-81ea-231623b30e63
DOI: 10.64898/2026.04.21.26350991

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