Article
HLA Associations of Intrathecal IgG Production against Specific Viruses in Multiple Sclerosis.
Annals of neurology - 1 Jun 2024
Neidhart Stephan, Vlad Benjamin, Hilty Marc, Högelin Klara Asplund, Ziegler Mario, Berenjeno-Correa Ernesto, Reichen Ina, Stridh Pernilla, Jelcic Ivan, Khademi Mohsen, Kockum Ingrid, Sospedra Mireia, Al Nimer Faiez, Martin Roland, Jelcic Ilijas
Abstract excerpt
OBJECTIVE: Specific human leucocyte antigen (HLA) alleles are not only associated with higher risk to develop multiple sclerosis (MS) and other autoimmune diseases, but also with the severity of various viral and bacterial infections. Here, we analyzed the most specific biomarker for MS, that is, the polyspecific intrathecal IgG antibody production against measles, rubella, and varicella zoster virus (MRZ...
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