Article
Genetics of immune response to Epstein-Barr virus: prospects for multiple sclerosis pathogenesis.
Brain : a journal of neurology - 3 Oct 2024
Huang Jesse, Tengvall Katarina, Lima Izaura Bomfim, Hedström Anna Karin, Butt Julia, Brenner Nicole, Gyllenberg Alexandra, Stridh Pernilla, Khademi Mohsen, Ernberg Ingemar, Al Nimer Faiez, Manouchehrinia Ali, Hillert Jan, Alfredsson Lars, Andersen Oluf, Sundström Peter, Waterboer Tim, Olsson Tomas, Kockum Ingrid
Abstract excerpt
Epstein-Barr virus (EBV) infection has been advocated as a prerequisite for developing multiple sclerosis (MS) and possibly the propagation of the disease. However, the precise mechanisms for such influences are still unclear. A large-scale study investigating the host genetics of EBV serology and related clinical manifestations, such as infectious mononucleosis (IM), may help us better understand the role of EBV...
Topics
- Humans
- Multiple Sclerosis
- Male
- Female
- Herpesvirus 4, Human
- Adult
- Epstein-Barr Virus Nuclear Antigens
- Epstein-Barr Virus Infections
- Antibodies, Viral