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Article

Elevated EBNA-1 IgG in MS is associated with genetic MS risk variants

14 Oct 2017

Abstract excerpt

OBJECTIVE: To assess whether MS genetic risk polymorphisms (single nucleotide polymorphism [SNP]) contribute to the enhanced humoral immune response against Epstein-Barr virus (EBV) infection in patients with MS. METHODS: Serum anti-EBV nuclear antigen 1 (EBNA-1) and early antigen D (EA-D) immunoglobulin γ (IgG) levels were quantitatively determined in 668 genotyped patients with MS and 147 healthy controls....

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PMID: 29379819
DOI: 10.1212/nxi.0000000000000406

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