Article
Oligoclonal band phenotypes in MS differ in their HLA class II association, while specific KIR ligands at HLA class I show association to MS in general.
Journal of neuroimmunology - 15 Sept 2014
Gustavsen Marte W, Viken Marte K, Celius Elisabeth G, Berge Tone, Mero Inger-Lise, Berg-Hansen Pål, Aarseth Jan H, Myhr Kjell-Morten, Søndergaard Helle B, Sellebjerg Finn, Oturai Annette B, Hillert Jan, Alfredsson Lars, Olsson Tomas, Kockum Ingrid, Lie Benedicte A, Harbo Hanne F
Abstract excerpt
Multiple sclerosis (MS) patients have been reported to have different HLA class II allele profiles depending on oligoclonal bands (OCBs) in the cerebrospinal fluid, but HLA class I alleles and killer cell immunoglobulin-like receptor (KIR) ligands have not been studied. We investigated the association of HLA alleles and KIR ligands according to OCB status in MS patients (n=3876). Specific KIR ligands were...
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