Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

An essential protease, FtsH, influences daptomycin resistance acquisition in Enterococcus faecalis.

Molecular microbiology - 1 May 2024

Nair Zeus Jaren, Gao Iris Hanxing, Firras Aslam, Chong Kelvin Kian Long, Hill Eric D, Choo Pei Yi, Colomer-Winter Cristina, Chen Qingyan, Manzano Caroline, Pethe Kevin, Kline Kimberly A

Abstract excerpt

Daptomycin is a last-line antibiotic commonly used to treat vancomycin-resistant Enterococci, but resistance evolves rapidly and further restricts already limited treatment options. While genetic determinants associated with clinical daptomycin resistance (DAPR) have been described, information on factors affecting the speed of DAPR acquisition is limited. The multiple peptide resistance factor (MprF), a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anti-Bacterial Agents
Share to Bacterial Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Daptomycin

Share to Drug Resistance, Bacterial

Share to Enterococcus faecalis

Share to Methicillin-Resistant Staphylococcus aureus

Share to Microbial Sensitivity Tests

Share to Peptide Hydrolases

Source

Identifiers

PMID: 38527904
DOI: 10.1111/mmi.15253

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

An essential protease, FtsH, influences daptomycin resistance acquisition in Enterococcus faecalis.PMID 38527904Read ↗

An essential protease, FtsH, influences daptomycin resistance acquisition in <i>Enterococcus faecalis</i>Semantic proximity Read ↗

LiaR‐independent pathways to daptomycin resistance in Enterococcus faecalis reveal a multilayer defense against cell envelope antibioticsSemantic proximity Read ↗

Role of mprF1 and mprF2 in the Pathogenicity of Enterococcus faecalisSemantic proximity Read ↗

Differential daptomycin resistance development in Staphylococcus aureus strains with active and mutated gra regulatory systems.Semantic proximity Read ↗

Antimicrobial sensing coupled with cell membrane remodeling mediates antibiotic resistance and virulence in <i>Enterococcus faecalis</i>Semantic proximity Read ↗

Heterogeneity of mprF sequences in methicillin-resistant Staphylococcus aureus clinical isolates: role in cross-resistance between daptomycin and host defense antimicrobial peptides.Semantic proximity Read ↗

Daptomycin resistance in <i>Enterococcus faecium</i> can be delayed by disruption of the LiaFSR stress response pathwaySemantic proximity Read ↗

Defective pgsA contributes to increased membrane fluidity and cell wall thickening in Staphylococcus aureus with high-level daptomycin resistance.Semantic proximity Read ↗

Whole-genome analysis of a daptomycin-susceptible enterococcus faecium strain and its daptomycin-resistant variant arising during therapy.Semantic proximity Read ↗

Evolution of <i>Enterococcus faecium</i> to A Combination of Daptomycin and Fosfomycin Reveals Distinct and Diverse Adaptive StrategiesSemantic proximity Read ↗

Environment Shapes the Accessible Daptomycin Resistance Mechanisms in <i>Enterococcus faecium</i>Semantic proximity Read ↗

Genetic Basis for Daptomycin Resistance in EnterococciSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.