Back to search

Article

Environment Shapes the Accessible Daptomycin Resistance Mechanisms in <i>Enterococcus faecium</i>

2019-04-12

Abstract excerpt

Daptomycin binds to bacterial cell membranes and disrupts essential cell envelope processes leading to cell death. Bacteria respond to daptomycin by altering their cell envelopes to either decrease antibiotic binding to the membrane or by diverting binding away from vulnerable septal targets to remodeled anionic phospholipid membrane patches. In Enterococcus faecalis , daptomycin resistance is typically coordinat...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
bfbacd33-b5ec-5e71-8450-2a4c906eb6a4
DOI
10.1101/607440
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Environment Shapes the Accessible Daptomycin Resistance Mechanisms in <i>Enterococcus faecium</i>DOI 10.1101/607440
Daptomycin resistance in <i>Enterococcus faecium</i> can be delayed by disruption of the LiaFSR stress response pathwaySemantic proximity
LiaR‐independent pathways to daptomycin resistance in Enterococcus faecalis reveal a multilayer defense against cell envelope antibioticsSemantic proximity
Antimicrobial sensing coupled with cell membrane remodeling mediates antibiotic resistance and virulence in <i>Enterococcus faecalis</i>Semantic proximity
Novel regulatory logic in the antibiotic resistance response of <i>Enterococcus faecalis</i> against cell envelope targeting antibioticsSemantic proximity
Molecular basis of cell membrane adaptation in daptomycin-resistant Enterococcus faecalisSemantic proximity
LiaX is a surrogate marker for cell-envelope stress and daptomycin non-susceptibility in <i>Enterococcus faecium</i>Semantic proximity
Acquisition of Daptomycin Resistance by Enterococcus faecium Confers Collateral Sensitivity to GlycopeptidesSemantic proximity
Heteroresistance in <i>Enterococcus faecalis</i> is prevalent for key antibiotics and mainly caused by mutationsSemantic proximity
Genetic basis for in vivo daptomycin resistance in enterococci.Semantic proximity
Reduced chlorhexidine and daptomycin susceptibility arises in vancomycin-resistant <i>Enterococcus faecium</i> after serial chlorhexidine exposureSemantic proximity
Evolution of <i>Enterococcus faecium</i> to A Combination of Daptomycin and Fosfomycin Reveals Distinct and Diverse Adaptive StrategiesSemantic proximity
Rising daptomycin resistance in <i>Enterococcus faecium</i> across a hospital system occurred via rampant recurrent evolution and occasional transmission between patientsSemantic proximity
Select a neighboring publication to make it the new centre.