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Evolution of <i>Enterococcus faecium</i> to A Combination of Daptomycin and Fosfomycin Reveals Distinct and Diverse Adaptive Strategies

2021-12-21

Abstract excerpt

Infections caused by vancomycin-resistant Enterococcus faecium (VREfm) are an important public health threat. VREfm have become increasingly resistant to the front-line antibiotic, daptomycin (DAP). As such, the use of DAP combination therapies (like fosfomycin [FOS]), has received increased attention. Antibiotic combinations could extend the efficacy of current available antibiotics and potentially delay the ons...

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Literature Corpus work
f34679b6-a70b-5d83-a6d7-474a1e23e6c1
DOI
10.1101/2021.12.20.473606
Open publication

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Evolution of <i>Enterococcus faecium</i> to A Combination of Daptomycin and Fosfomycin Reveals Distinct and Diverse Adaptive StrategiesDOI 10.1101/2021.12.20.473606
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