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Role of mprF1 and mprF2 in the Pathogenicity of Enterococcus faecalis

18 Jun 2012

Abstract excerpt

BACKGROUND: Enterococcus faecalis is one of the leading causes of nosocomial infections. Due to its innate and acquired resistance to most antibiotics, identification of new targets for antimicrobial treatment of E. faecalis is a high priority. The multiple peptide resistance factor MprF, which was first described in Staphylococcus aureus, modifies phosphatidylglycerol with lysin and reduces the negative charge...

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PMID: 22723861
DOI: 10.1371/journal.pone.0038458

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