Article
Genomic stability disorders: from budding yeast to humans.
Frontiers in bioscience (Scholar edition) - 1 Jan 2013
Hoch Nicolas Carlos, Lai Xianning, Heierhorst Jörg
Abstract excerpt
Fundamental aspects of eukaryotic molecular and cellular biology are extensively studied in the budding yeast Saccharomyces cerevisiae. Genome maintenance pathways are highly conserved and research into a number of human genetic disorders with increased genome instability and cancer predisposition have benefited greatly from studies in budding yeast. Here, we present some of the examples where yeast research into...
Topics
- DNA Damage
- Genetic Predisposition to Disease
- Genome, Fungal
- Genomic Instability
- Humans
- Saccharomyces cerevisiae
- Telomere