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Article

Dietary fats and the APOE-e4 risk allele in relation to cognitive decline: a longitudinal investigation in a biracial population sample.

The journal of nutrition, health & aging - 1 May 2024

Liu Xiaoran, Beck Todd, Dhana Klodian, Tangney Christy C, Desai Pankaja, Krueger Kristin, Evans Denis A, Rajan Kumar B

Abstract excerpt

BACKGROUND: APOE-e4 is the strongest genetic risk factor for Alzheimer's disease. However, the influence of APOE-e4 on dietary fat intake and cognition has not been investigated. OBJECTIVE: We aim to examine the association of types of dietary fat and their association to cognitive decline among those with and without the APOE-e4 allele. METHODS: The study included 3,360 Chicago Health and Aging Project (CHAP)...

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Identifiers

PMID: 38507884
DOI: 10.1016/j.jnha.2024.100211
PMCID: PMC11623058

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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