Article
Race, APOE genotypes, and cognitive decline among middle-aged urban adults.
Alzheimer's research & therapy - 30 Jun 2021
Beydoun May A, Weiss Jordan, Beydoun Hind A, Hossain Sharmin, Maldonado Ana I, Shen Botong, Evans Michele K, Zonderman Alan B
Abstract excerpt
BACKGROUND: Associations of Apolipoprotein (APOE) ε2 or ε4 (APOE2 or APOE4) dosages with cognitive change may differ across racial groups. METHODS: Longitudinal data on 1770 middle-aged White and African American adults was compiled from the Healthy Aging in Neighborhoods of Diversity across the Life Span (HANDLS 2004-2013) study. APOE2 and APOE4 dosages were the two main exposures, while v1 and annual rate of...
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