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Article

Interactions Between Blood Nutritional Biomarkers and Apolipoprotein E ε4 in the Progression of Mild Cognitive Impairment in Alzheimer's Disease.

Nutrients - 16 Apr 2026

Lawal Rasheedat, Kumar Sanjay, Chigevenga Rosemary, Coe Shelly

Abstract excerpt

BACKGROUND/OBJECTIVES: Mild cognitive impairment (MCI), the prodromal stage of Alzheimer's disease, may be influenced by nutritional status and genetic susceptibility. This systematic review synthesised evidence on how nutritional biomarkers interact with genetic variants, particularly APOE ε4, to influence cognitive outcomes in individuals with MCI. METHODS: Following PRISMA 2020 guidelines, seven studies were...

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Identifiers

PMID: 42075076
DOI: 10.3390/nu18081263
PMCID: PMC13119481

Genes

APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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