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Article

Temperature impacts SARS-CoV-2 spike fusogenicity and evolution

27 Feb 2024

Abstract excerpt

ABSTRACT SARS-CoV-2 infects both the upper and lower respiratory tracts, which are characterized by different temperatures (33°C and 37°C, respectively). In addition, fever is a common COVID-19 symptom. SARS-CoV-2 has been shown to replicate more efficiently at low temperatures, but the effect of temperature on different viral proteins remains poorly understood. Here, we investigate how temperature affects the...

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PMID: 38411986
DOI: 10.1128/mbio.03360-23

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