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Article

HDL levels modulate the impact of type 2 diabetes susceptibility alleles in older adults.

Lipids in health and disease - 22 Feb 2024

Sullivan Siobhán O ', Al Hageh Cynthia, Henschel Andreas, Chacar Stephanie, Abchee Antoine, Zalloua Pierre, Nader Moni

Abstract excerpt

BACKGROUND: Type 2 Diabetes (T2D) is influenced by genetic, environmental, and ageing factors. Ageing pathways exacerbate metabolic diseases. This study aimed to examine both clinical and genetic factors of T2D in older adults. METHODS: A total of 2,909 genotyped patients were enrolled in this study. Genome Wide Association Study was conducted, comparing T2D patients to non-diabetic older adults aged ≥ 60, ≥ 65,...

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Share to Alleles
Share to Cholesterol, HDL

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Diabetes Mellitus, Type 2

Share to Genetic Predisposition to Disease

Share to Genome-Wide Association Study

Share to Polymorphism, Single Nucleotide

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Source

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Identifiers

PMID: 38389069
DOI: 10.1186/s12944-024-02039-7
PMCID: PMC10882764

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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