Article
Multi-ethnic genome-wide association study identifies novel locus for type 2 diabetes susceptibility.
European journal of human genetics : EJHG - 1 Aug 2016
Cook James P, Morris Andrew P
Abstract excerpt
Genome-wide association studies (GWAS) have traditionally been undertaken in homogeneous populations from the same ancestry group. However, with the increasing availability of GWAS in large-scale multi-ethnic cohorts, we have evaluated a framework for detecting association of genetic variants with complex traits, allowing for population structure, and developed a powerful test of heterogeneity in allelic effects...
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