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Article

Type-2 diabetes with low LDL-C: genetic insights into a unique phenotype

2019-11-13

Abstract excerpt

Although hyperlipidemia is traditionally considered a risk factor for type-2 diabetes (T2D), evidence has emerged from statin trials and candidate gene investigations suggesting that lower LDL-C increases T2D risk. We thus sought to comprehensively examine the phenotypic and genotypic relationships of LDL-C with T2D. Using data from the UK Biobank, we found that LDL-C was negatively associated with T2D (OR=0.43[0....

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Literature Corpus work
15afa420-ae97-5fa3-b59e-fee426bc4bc2
DOI
10.1101/837013
Open publication

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Type-2 diabetes with low LDL-C: genetic insights into a unique phenotypeDOI 10.1101/837013
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