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Article

AI-assisted proofreading of RNA splicing.

Genes & development - 26 Dec 2023

Guerra-Moreno Ángel, Valcárcel Juan

Abstract excerpt

RNA helicases orchestrate proofreading mechanisms that facilitate accurate intron removal from pre-mRNAs. How these activities are recruited to spliceosome/pre-mRNA complexes remains poorly understood. In this issue of Genes & Development, Zhang and colleagues (pp. 968-983) combine biochemical experiments with AI-based structure prediction methods to generate a model for the interaction between SF3B1, a core...

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Identifiers

PMID: 38092520
DOI: 10.1101/gad.351373.123
PMCID: PMC10760631

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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