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Article

Total Cholesterol and APOE-Related Risk for Alzheimer's Disease in the Alzheimer's Disease Neuroimaging Initiative.

Journal of Alzheimer's disease : JAD - 1 Jan 2022

Dunk Michelle M, Driscoll Ira

Abstract excerpt

BACKGROUND: APOEɛ4 allele confers greatest genetic risk for Alzheimer's disease (AD), yet mechanisms underlying this risk remain elusive. APOE is involved in lipid metabolism, and literature suggest relationships between high total cholesterol, APOE, and AD. Further investigation is needed to elucidate the potential role of total cholesterol in AD risk. OBJECTIVE: To investigate the relationship between total...

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Identifiers

PMID: 34958023
DOI: 10.3233/JAD-215091
PMCID: PMC10442640

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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