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Article

Aneuploidy Landscape in Precursors of Ovarian Cancer

4 Dec 2023

Abstract excerpt

PURPOSE: Serous tubal intraepithelial carcinoma (STIC) is now recognized as the main precursor of ovarian high-grade serous carcinoma (HGSC). Other potential tubal lesions include p53 signatures and tubal intraepithelial lesions. We aimed to investigate the extent and pattern of aneuploidy in these epithelial lesions and HGSC to define the features that characterize stages of tumor initiation and progression....

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Identifiers

PMID: 38048050
DOI: 10.1158/1078-0432.ccr-23-0932

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