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Article

Next-Generation Sequencing of Tubal Intraepithelial Carcinomas.

JAMA oncology - 1 Nov 2015

McDaniel Andrew S, Stall Jennifer N, Hovelson Daniel H, Cani Andi K, Liu Chia-Jen, Tomlins Scott A, Cho Kathleen R

Abstract excerpt

IMPORTANCE: High-grade serous carcinoma (HGSC) is the most prevalent and lethal form of ovarian cancer. HGSCs frequently arise in the distal fallopian tubes rather than the ovary, developing from small precursor lesions called serous tubal intraepithelial carcinomas (TICs, or more specifically, STICs). While STICs have been reported to harbor TP53 mutations, detailed molecular characterizations of these lesions...

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Source

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Identifiers

PMID: 26181193
DOI: 10.1001/jamaoncol.2015.1618
PMCID: PMC4935931

Genes

BRCA1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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