Article
Polygenic risk scores.
Seminars in arthritis and rheumatism - 1 Feb 2024
Brown Matthew A
Abstract excerpt
Polygenic risk scores (PRS) estimate an individual's genetic risk for a disease or trait compared to a matched population. For many rheumatic diseases PRS have been developed that have discriminatory capacity better than some widely used biomarkers, and in some cases are the most discriminatory tests available. These PRS assessments do not rely on the disease being present or its activity level, making them...
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