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Article

Genetic Risk Scores for the Clinical Rheumatologist.

Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases - 1 Jan 2025

Wheeler Austin M, Riley Thomas R, Merriman Tony R

Abstract excerpt

BACKGROUND/HISTORICAL PERSPECTIVE: The advent of genome-wide sequencing and large-scale genetic epidemiological studies has led to numerous opportunities for the application of genetics in clinical medicine. Leveraging this information toward the formation of clinically useful tools has been an ongoing research goal in this area. A genetic risk score (GRS) is a measure that attempts to estimate the cumulative...

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PMID: 39454094
DOI: 10.1097/RHU.0000000000002152

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