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Article

Utility of polygenic risk scores to aid in the diagnosis of rheumatic diseases.

Best practice & research. Clinical rheumatology - 1 Dec 2024

Santiago-Lamelas Lucía, Dos Santos-Sobrín Raquel, Carracedo Ángel, Castro-Santos Patricia, Díaz-Peña Roberto

Abstract excerpt

Rheumatic diseases (RDs) are characterized by autoimmunity and autoinflammation and are recognized as complex due to the interplay of multiple genetic, environmental, and lifestyle factors in their pathogenesis. The rapid advancement of genome-wide association studies (GWASs) has enabled the identification of numerous single nucleotide polymorphisms (SNPs) associated with RD susceptibility. Based on these SNPs,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 38997822
DOI: 10.1016/j.berh.2024.101973

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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