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Article

The Application of Genetic Risk Scores in Rheumatic Diseases: A Perspective.

Genes - 1 Dec 2023

Vaskimo Lotta M, Gomon Georgy, Naamane Najib, Cordell Heather J, Pratt Arthur, Knevel Rachel

Abstract excerpt

Modest effect sizes have limited the clinical applicability of genetic associations with rheumatic diseases. Genetic risk scores (GRSs) have emerged as a promising solution to translate genetics into useful tools. In this review, we provide an overview of the recent literature on GRSs in rheumatic diseases. We describe six categories for which GRSs are used: (a) disease (outcome) prediction, (b) genetic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 38136989
DOI: 10.3390/genes14122167
PMCID: PMC10743278

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