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Ugeskrift for laeger - 25 Sept 2023

Terkelsen Thorkild, Hansen Thomas Folkmann, Herlin Morten Krogh, Djursby Malene, Nyegaard Mette, Pedersen Inge Søkilde, Lildballe Dorte Launholt, Færgeman Søren Lejsted, Sunde Lone, Hauberg Mads Engel

Abstract excerpt

Polygenic risk scores (PRS) identify at-risk individuals for many common diseases. A discussion of strengths and limitations is carried out in this review. PRS complement traditional genetic testing and have shown utility in establishing a proper diagnosis and guiding primary and secondary prevention. Some individuals with high PRS have risks similar to those with monogenic predisposition. Limitations include...

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PMID: 37873989

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