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Article

APOE genotype and sex modulate Alzheimer’s disease pathology in aged EFAD transgenic mice

31 Oct 2023

Abstract excerpt

Increasing evidence supports that age, APOE and sex interact to modulate Alzheimer’s disease (AD) risk, however the underlying pathways are unclear. One way that AD risk factors may modulate cognition is by impacting amyloid beta (Aβ) accumulation as plaques, and/or neuroinflammation Therefore, the goal of the present study was to evaluate the extent to which age, APOE and sex modulate Aβ pathology,...

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Identifiers

PMID: 38020764
DOI: 10.3389/fnagi.2023.1279343

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