Article

Sex differences in behaviour and molecular pathology in the 5XFAD model

2021-04-29

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> The prevalence of Alzheimer’s Disease (AD) is greater in women compared to men, but the reasons for this remain unknown. This sex difference has been widely neglected in experimental studies using transgenic mouse models of AD. <h4>Objective</h4> Here, we studied behaviour and molecular pathology of 5-month-old 5XFAD mice, which express mutated human amyloid precursor prote...

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Literature Corpus work: aa98b3cd-9090-5ec8-9adf-ffa009884c1b
DOI: 10.1101/2021.04.29.440396

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