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Benchmarking of local genetic correlation estimation methods using summary statistics from genome-wide association studies.

Briefings in bioinformatics - 22 Sept 2023

Zhang Chi, Zhang Yiliang, Zhang Yunxuan, Zhao Hongyu

Abstract excerpt

Local genetic correlation evaluates the correlation of additive genetic effects between different traits across the same genetic variants at a genomic locus. It has been proven informative for understanding the genetic similarities of complex traits beyond that captured by global genetic correlation calculated across the whole genome. Several summary-statistics-based approaches have been developed for estimating...

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PMID: 37974509
DOI: 10.1093/bib/bbad407
PMCID: PMC10654488

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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