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Article

Fast estimation of genetic correlation for biobank-scale data.

American journal of human genetics - 6 Jan 2022

Wu Yue, Burch Kathryn S, Ganna Andrea, Pajukanta Päivi, Pasaniuc Bogdan, Sankararaman Sriram

Abstract excerpt

Genetic correlation is an important parameter in efforts to understand the relationships among complex traits. Current methods that analyze individual genotype data for estimating genetic correlation are challenging to scale to large datasets. Methods that analyze summary data, while being computationally efficient, tend to yield estimates of genetic correlation with reduced precision. We propose SCORE (scalable...

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Identifiers

PMID: 34861179
DOI: 10.1016/j.ajhg.2021.11.015
PMCID: PMC8764132

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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