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Article

Comparison of methods for estimating genetic correlation between complex traits using GWAS summary statistics.

Briefings in bioinformatics - 2 Sept 2021

Zhang Yiliang, Cheng Youshu, Jiang Wei, Ye Yixuan, Lu Qiongshi, Zhao Hongyu

Abstract excerpt

Genetic correlation is the correlation of phenotypic effects by genetic variants across the genome on two phenotypes. It is an informative metric to quantify the overall genetic similarity between complex traits, which provides insights into their polygenic genetic architecture. Several methods have been proposed to estimate genetic correlation based on data collected from genome-wide association studies (GWAS)....

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PMID: 33497438
DOI: 10.1093/bib/bbaa442
PMCID: PMC8425307

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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