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Article

Local Genetic Correlation Gives Insights into the Shared Genetic Architecture of Complex Traits.

American journal of human genetics - 2 Nov 2017

Shi Huwenbo, Mancuso Nicholas, Spendlove Sarah, Pasaniuc Bogdan

Abstract excerpt

Although genetic correlations between complex traits provide valuable insights into epidemiological and etiological studies, a precise quantification of which genomic regions disproportionately contribute to the genome-wide correlation is currently lacking. Here, we introduce ρ-HESS, a technique to quantify the correlation between pairs of traits due to genetic variation at a small region in the genome. Our...

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Identifiers

PMID: 29100087
DOI: 10.1016/j.ajhg.2017.09.022
PMCID: PMC5673668

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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