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Article

An integrated framework for local genetic correlation analysis.

Nature genetics - 1 Mar 2022

Werme Josefin, van der Sluis Sophie, Posthuma Danielle, de Leeuw Christiaan A

Abstract excerpt

Genetic correlation (rg) analysis is used to identify phenotypes that may have a shared genetic basis. Traditionally, rg is studied globally, considering only the average of the shared signal across the genome, although this approach may fail when the rg is confined to particular genomic regions or in opposing directions at different loci. Current tools for local rg analysis are restricted to analysis of two...

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PMID: 35288712
DOI: 10.1038/s41588-022-01017-y

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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