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Article

Prophylactic Salpingo-Oophorectomy and Survival After BRCA1/2 Breast Cancer Resection.

JAMA surgery - 1 Dec 2023

Martelli Gabriele, Barretta Francesco, Vernieri Claudio, Folli Secondo, Pruneri Giancarlo, Segattini Silvia, Trapani Anna, Carolla Claudia, Spatti Gianbattista, Miceli Rosalba, Ferraris Cristina

Abstract excerpt

Importance: Few studies have investigated whether prophylactic salpingo-oophorectomy (PSO) for patients with previously resected breast cancer who carry pathogenic germline BRCA1 or BRCA2 variants is associated with a reduced risk of cancer-specific death. Objective: To assess the association of PSO and prophylactic mastectomy (PM) with prognosis after quadrantectomy or mastectomy as primary treatment for...

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Identifiers

PMID: 37792368
DOI: 10.1001/jamasurg.2023.4770
PMCID: PMC10551816

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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