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Article

Differences among a Portuguese cohort of BRCA pathogenic/likely pathogenic variants carriers choosing risk-reducing mastectomy or intensive breast surveillance.

Journal of cancer research and clinical oncology - 1 Aug 2023

Torres Sandra, Peleteiro Bárbara, Magalhães André, Garrido Luzia, Costa Susy, Fougo José Luís

Abstract excerpt

PURPOSE: Women with BRCA1 and BRCA2 (BRCA1/2) pathogenic/likely pathogenic (P/LP) variants have a higher risk to develop breast and ovarian cancer. In structured high-risk clinics, risk-reducing measures are adopted. This study aimed at characterizing these women and identify factors that may have influenced their choice between risk reduction mastectomy (RRM) and intensive breast surveillance (IBS). METHODS:...

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Identifiers

PMID: 36971799
DOI: 10.1007/s00432-023-04663-9
PMCID: PMC10374730

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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