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Article

Risk-reducing bilateral salpingo-oophorectomy in women with BRCA1 or BRCA2 mutations.

The Cochrane database of systematic reviews - 24 Aug 2018

Eleje George U, Eke Ahizechukwu C, Ezebialu Ifeanyichukwu U, Ikechebelu Joseph I, Ugwu Emmanuel O, Okonkwo Onyinye O

Abstract excerpt

BACKGROUND: The presence of deleterious mutations in breast cancer 1 gene (BRCA1) or breast cancer 2 gene (BRCA2) significantly increases the risk of developing some cancers, such as breast and high-grade serous cancer (HGSC) of ovarian, tubal and peritoneal origin. Risk-reducing salpingo-oophorectomy (RRSO) is usually recommended to BRCA1 or BRCA2 carriers after completion of childbearing. Despite prior...

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Source

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Identifiers

PMID: 30141832
DOI: 10.1002/14651858.CD012464.pub2
PMCID: PMC6513554

Genes

BRCA2
BRCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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