Article
Association of Risk-Reducing Salpingo-Oophorectomy With Breast Cancer Risk in Women With BRCA1 and BRCA2 Pathogenic Variants.
JAMA oncology - 1 Apr 2021
Choi Yun-Hee, Terry Mary Beth, Daly Mary B, MacInnis Robert J, Hopper John L, Colonna Sarah, Buys Saundra S, Andrulis Irene L, John Esther M, Kurian Allison W, Briollais Laurent
Abstract excerpt
IMPORTANCE: Women with pathogenic variants in BRCA1 and BRCA2 are at high risk of developing breast and ovarian cancers. They usually undergo intensive cancer surveillance and may also consider surgical interventions, such as risk-reducing mastectomy or risk-reducing salpingo-oophorectomy (RRSO). Risk-reducing salpingo-oophorectomy has been shown to reduce ovarian cancer risk, but its association with breast...
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