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Article

Low Frequency of Aflatoxin Induced TP53 Gene Codon 249 Mutation in Hepatocellular Carcinoma from Egyptian Patients Living in the Nile Delta Region.

Asian Pacific journal of cancer prevention : APJCP - 1 Sept 2023

Mosbeh Asmaa, Abdelmaguid Waleed, Ezzat Sameera, Kohla Mohamed, Sultan Mervat M, Abdel-Rahman Mohamed H

Abstract excerpt

OBJECTIVE: Study the frequency of codon 7 (c.747 G>T, p. R249S) mutation associated with Aflatoxin B1 (AFB1) exposure in Egyptian patients with hepatocellular carcinoma (HCC). METHODS: We utilized restriction fragment polymorphism and direct sequencing to assess codon 7 mutations in 104 hepatocellular carcinomas. The expression of TP53 protein in the tumors were assessed in 44 tumors by a monoclonal rabbit...

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Identifiers

PMID: 37774068
DOI: 10.31557/APJCP.2023.24.9.3165
PMCID: PMC10762730

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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