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Article

P53 codon 249 mutation in hepatocellular carcinomas from Nigeria.

African journal of medicine and medical sciences - 1 Jan 2000

Ndububa D A, Yakicier C M, Ojo O S, Adeodu O O, Rotimi O, Ogunbiyi O, Ozturk M

Abstract excerpt

Mutations of p53 tumour suppressor gene often occur in hepatocellular carcinoma and, in particular, codon 249 hot-spot mutation is displayed by hepatocellular carcinomas occurring in hepatitis B virus-endemic areas with high dietary aflatoxin intake. This study was done to determine the frequency of p53 codon 249 mutation in hepato-cellular carcinoma in Nigerian patients with this tumour. Tumour samples were...

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PMID: 14510167

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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