Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Assessing HLA imputation accuracy in a West African population.

PloS one - 1 Jan 2023

Nanjala Ruth, Mbiyavanga Mamana, Hashim Suhaila, de Villiers Santie, Mulder Nicola

Abstract excerpt

The Human Leukocyte Antigen (HLA) region plays an important role in autoimmune and infectious diseases. HLA is a highly polymorphic region and thus difficult to impute. We, therefore, sought to evaluate HLA imputation accuracy, specifically in a West African population, since they are understudied and are known to harbor high genetic diversity. The study sets were selected from 315 Gambian individuals within the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genome-Wide Association Study
Share to Genotype
Share to Histocompatibility Antigens Class I

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Histocompatibility Antigens Class II

Share to HLA Antigens

Share to HLA-B Antigens

Share to Polymorphism, Single Nucleotide

Source

Open in PubMed Open full text

Identifiers

PMID: 37768905
DOI: 10.1371/journal.pone.0291437
PMCID: PMC10538777

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Assessing HLA imputation accuracy in a West African population.PMID 37768905Read ↗

Assessing HLA imputation accuracy in a West African populationSemantic proximity Read ↗

Human leucocyte antigen class I and II imputation in a multiracial population.Semantic proximity Read ↗

Comparison of HLA allelic imputation programs.Semantic proximity Read ↗

A statistical genetics guide to identifying HLA alleles driving complex diseaseSemantic proximity Read ↗

HLA-IMPUTER: an easy to use web application for HLA imputation and association analysis using population-specific reference panels.Semantic proximity Read ↗

Performance of HLA allele prediction methods in African Americans for class II genes HLA-DRB1, -DQB1, and -DPB1.Semantic proximity Read ↗

Significant variation between SNP-based HLA imputations in diverse populations: the last mile is the hardest.Semantic proximity Read ↗

Accurate multi-population imputation of MICA, MICB, HLA-E, HLA-F and HLA-G alleles from genome SNP dataSemantic proximity Read ↗

Practical Use of Methods for Imputation of HLA Alleles from SNP Genotype DataSemantic proximity Read ↗

Uncovering genetic diversity and admixture of British Africans with HLA alleles inferred from whole genome sequencing.Semantic proximity Read ↗

Evaluation of HLA-DRB1 imputation using a Finnish dataset.Semantic proximity Read ↗

Tutorial: a statistical genetics guide to identifying HLA alleles driving complex disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.