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Accurate multi-population imputation of MICA, MICB, HLA-E, HLA-F and HLA-G alleles from genome SNP data

2023-12-07

Abstract excerpt

In addition to the classical HLA genes, the major histocompatibility complex (MHC) harbors a high number of other polymorphic genes with less established roles in disease associations and transplantation matching. To facilitate studies of the non-classical and non-HLA genes in large patient and biobank cohorts, we trained imputation models for MICA, MICB, HLA-E, HLA-F and HLA-G alleles on genome SNP array data. We...

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Literature Corpus work
d1da98d6-4d52-5224-8a16-707c919ffa0f
DOI
10.1101/2023.12.05.570226
Open publication

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Accurate multi-population imputation of MICA, MICB, HLA-E, HLA-F and HLA-G alleles from genome SNP dataDOI 10.1101/2023.12.05.570226
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