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Article

Evaluation of HLA-DRB1 imputation using a Finnish dataset.

Tissue antigens - 1 May 2014

Vlachopoulou E, Lahtela E, Wennerström A, Havulinna A S, Salo P, Perola M, Salomaa V, Nieminen M S, Sinisalo J, Lokki M-L

Abstract excerpt

Owing to the vast amount of alleles, high-resolution human leukocyte antigen (HLA) typing is expensive and time-consuming. Scientists have attempted to develop computational approaches to define HLA alleles with high confidence. We tested the reliability of HLA*IMP and SNP2HLA for imputing HLA-DRB1 alleles in a Finnish material (n=161). The per-individual success rates varied between 16.68% and 25.4% using both...

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Identifiers

PMID: 24666112
DOI: 10.1111/tan.12343

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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