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Virus-specific TRM cells of both donor and recipient origin reside in human kidney transplants

26 Sept 2023

Abstract excerpt

Tissue-resident lymphocytes (TRLs) are critical for local protection against viral pathogens in peripheral tissue. However, it is unclear if TRLs perform a similar role in transplanted organs under chronic immunosuppressed conditions. In this study, we aimed to characterize the TRL compartment in human kidney transplant nephrectomies and examine its potential role in antiviral immunity. The TRL compartment of...

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Share to Cytomegalovirus and herpesvirus research
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Share to Renal Transplantation Outcomes and Treatments

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PMID: 37751288
DOI: 10.1172/jci.insight.172681

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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