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Article

Signatures and Specificity of Tissue-Resident Lymphocytes Identified in Human Renal Peritumor and Tumor Tissue.

Journal of the American Society of Nephrology : JASN - 1 Sept 2021

Dornieden Theresa, Sattler Arne, Pascual-Reguant Anna, Ruhm Annkathrin Helena, Thiel Lion Gabriel, Bergmann Yasmin Samira, Thole Linda Marie Laura, Köhler Ralf, Kühl Anja Andrea, Hauser Anja Erika, Boral Sengül, Friedersdorff Frank, Kotsch Katja

Abstract excerpt

BACKGROUND: Tissue-resident memory T (TRM) cells are known to be important for the first line of defense in mucosa-associated tissues. However, the composition, localization, effector function, and specificity of TRM cells in the human kidney and their relevance for renal pathology have not been investigated. METHODS: Lymphocytes derived from blood, renal peritumor samples, and tumor samples were phenotypically...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34074699
DOI: 10.1681/ASN.2020101528
PMCID: PMC8729844

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