Article
NK and CD8+ T cell phenotypes predict onset and control of CMV viremia after kidney transplant.
JCI insight - 8 Nov 2021
Pickering Harry, Sen Subha, Arakawa-Hoyt Janice, Ishiyama Kenichi, Sun Yumeng, Parmar Rajesh, Ahn Richard S, Sunga Gemalene, Llamas Megan, Hoffmann Alexander, Deng Mario, Bunnapradist Suphamai, Schaenman Joanna M, Gjertson David W, Rossetti Maura, Lanier Lewis L, Reed Elaine F
Abstract excerpt
CMV causes mostly asymptomatic but lifelong infection. Primary infection or reactivation in immunocompromised individuals can be life-threatening. CMV viremia often occurs in solid organ transplant recipients and associates with decreased graft survival and higher mortality. Furthering understanding of impaired immunity that allows CMV reactivation is critical to guiding antiviral therapy and examining the effect...
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