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Single cell RNA-sequencing delineates CD8 + tissue resident memory T cells maintaining rejection in liver transplantation

1 Jan 2024

Abstract excerpt

Rationale: Understanding the immune mechanisms associated with liver transplantation (LT), particularly the involvement of tissue-resident memory T cells (TRMs), represents a significant challenge.Methods: This study employs a multi-omics approach to analyse liver transplant samples from both human (n = 17) and mouse (n = 16), utilizing single-cell RNA sequencing, bulk RNA sequencing, and immunological...

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Share to Immune Cell Function and Interaction
Share to Renal Transplantation Outcomes and Treatments
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PMID: 39239518
DOI: 10.7150/thno.96928

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