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Article

Discovery of cellular and genetic signatures of immune tolerance in kidney transplant recipients through single cell RNA sequencing analysis.

HLA - 1 Sept 2023

Bae Hyunjoo, Lee Hanbi, Ko Eun Jeong, Kim Chan-Duck, Lee Sang-Ho, Yang Chul Woo, Oh Eun-Jee, Chung Byung Ha

Abstract excerpt

The objective of this study was to uncover distinct cellular and genetic signatures of transplant operational tolerance (TOT) in kidney transplant recipients (KTRs) through single cell RNA sequencing (scRNA-seq) using peripheral blood mononuclear cells (PBMCs). PBMCs were isolated from 12 KTRs, including those with TOT (TOT, n = 4), stable allograft function on maintenance immunosuppression (STA, n = 4) and...

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Identifiers

PMID: 37038287
DOI: 10.1111/tan.15061

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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